3-iodotyrosine (3-IY) inhibits tyrosine hydroxylase that catalyzes levodopa (L-DOPA) formation from tyrosine. Iodotyrosine deiodinase enzyme deficiency leads to elevated levels of 3-IY in serum and urine in severe hypothyroidism and goiter. TH (tyrosine 3
Storage Temp
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Iodotyrosine coupled with di-iodotyrosine results in the synthesis of 3,5,3′-tri-iodothyronine (T3) or 3,3′,5′-tri-iodothyronine (rT3) Tyrosine hydroxylase inhibitor.
1.Qinhong Yin, Xiaolan Yang, Lihua Yang, Dezhi Yang, Yaling Yang, Yanqin Zhu. (2023) Cu, I-doped carbon dots as simulated nanozymes for the colorimetric detection of morphine in biological samples. ANALYTICAL BIOCHEMISTRY, 680 (115313). [PMID:37678583][10.1016/j.ab.2023.115313]
2.Xiao Li, Yan Xu, Dimei Ouyang, Kefan Ye, Yiwen Chen, Qiulan Li, Qinghai Xia, Xiaomei Wu, Yaling Yang. (2023) Copper- and iodine-doped nanozymes with simulated enzyme activity and efficient antifungal activity against Candida albicans. BIOCHEMICAL ENGINEERING JOURNAL, 191 (108791). [PMID:][10.1016/j.bej.2022.108791]
3.Yang Dezhi, Li Qiulan, Zhang Qian, Wang Yijie, Li Hong, Tammina Sai Kumar, Yang Yaling. (2022) A multifunctional nanozyme-based enhanced system for tert-butyl hydroquinone assay by surface-enhanced Raman scattering. MICROCHIMICA ACTA, 189 (1):(1-9). [PMID:34910256][10.1007/s00604-021-05135-y]
References
1.Qinhong Yin, Xiaolan Yang, Lihua Yang, Dezhi Yang, Yaling Yang, Yanqin Zhu. (2023) Cu, I-doped carbon dots as simulated nanozymes for the colorimetric detection of morphine in biological samples. ANALYTICAL BIOCHEMISTRY, 680 (115313). [PMID:37678583][10.1016/j.ab.2023.115313]
2.Xiao Li, Yan Xu, Dimei Ouyang, Kefan Ye, Yiwen Chen, Qiulan Li, Qinghai Xia, Xiaomei Wu, Yaling Yang. (2023) Copper- and iodine-doped nanozymes with simulated enzyme activity and efficient antifungal activity against Candida albicans. BIOCHEMICAL ENGINEERING JOURNAL, 191 (108791). [PMID:][10.1016/j.bej.2022.108791]
3.Yang Dezhi, Li Qiulan, Zhang Qian, Wang Yijie, Li Hong, Tammina Sai Kumar, Yang Yaling. (2022) A multifunctional nanozyme-based enhanced system for tert-butyl hydroquinone assay by surface-enhanced Raman scattering. MICROCHIMICA ACTA, 189 (1):(1-9). [PMID:34910256][10.1007/s00604-021-05135-y]
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