Immune checkpoint proteins
- Cemiplimab (anti-PD-1), Antibody of programmed cell death 1 (CD279)Associated targets: PDCD1
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Human
- Host species: Human
Cas#: 1801342-60-8Synonyms: hPD-1 | Protein PD-1 - Ipilimumab (anti-CTLA-4), Antibody of cytotoxic T-lymphocyte-associated protein 4 (CD152)Associated targets: CTLA4
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Cynomolgus monkey, Human, Mouse
- Host species: Human
Cas#: 477202-00-9 Compound CID: 167312542IUPAC Name: 3-butyl-4-hydroxy-5-methyl-5-(2-methylbuta-1,3-dienyl)thiophen-2-one;4-ethyl-2-methyl-2-(2-methylbuta-1,3-dienyl)-5-methylidenethiophen-3-ol;4-hydroxy-5-methyl-5-(2-methylbuta-1,3-dienyl)-3-[4-(4-methylphenyl)butyl]thiophen-2-one;4-hydroxy-5-methyl-5-(2-methylbuta-1,3-dienyl)-3-[2-(4-methylphenyl)ethyl]thiophen-2-one;4-hydroxy-5-methyl-5-(2-methylbuta-1,3-dienyl)-3-propylthiophen-2-oneSMILES: CCCCC1=C(C(SC1=O)(C)C=C(C)C=C)O.CCCC1=C(C(SC1=O)(C)C=C(C)C=C)O.CCC1=C(C(SC1=C)(C)C=C(C)C=C)O.CC1=CC=C(C=C1)CCCCC2=C(C(SC2=O)(C)C=C(C)C=C)O.CC1=CC=C(C=C1)CCCCC2=C(C(SC2=O)(C)C=C(C)C=C)O.CC1=CC=C(C=C1)CCCCC2=C(C(SC2=O)(C)C=C(C)C=C)O.CC1=CC=C(C=C1)CCCCC2=C(C(SC2=O)(C)C=C(C)C=C)O.CC1=CC=C(C=C1)CCC2=C(C(SC2=O)(C)C=C(C)C=C)O.CC1=CC=C(C=C1)CCC2=C(C(SC2=O)(C)C=C(C)C=C)OInChIKey: QZWDCJBBGBXHMW-UHFFFAOYSA-NInChI: InChI=1S/4C21H26O2S.2C19H22O2S.C14H20O2S.C13H18O2S.C13H18OS/c4*1-5-15(2)14-21(4)19(22)18(20(23)24-21)9-7-6-8-17-12-10-16(3)11-13-17;2*1-5-13(2)12-19(4)17(20)16(18(21)22-19)11-10-15-8-6-14(3)7-9-15;1-5-7-8-11-12(15)14(4,17-13(11)16)9-10(3)6-2;1-5-7-10-11(14)13(4,16-12(10)15)8-9(3)6-2;1-6-9(3)8-13(5)12(14)11(7-2)10(4)15-13/h4*5,10-14,22H,1,6-9H2,2-4H3;2*5-9,12,20H,1,10-11H2,2-4H3;6,9,15H,2,5,7-8H2,1,3-4H3;6,8,14H,2,5,7H2,1,3-4H3;6,8,14H,1,4,7H2,2-3,5H3 - Pembrolizumab (anti-PD-1), Antibody of programmed cell death 1 (CD279)Associated targets: PDCD1
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Cynomolgus monkey, Human
- Host species: Human
Cas#: 1374853-91-4 Compound CID: 168009853IUPAC Name: 1-butyl-4-propylpiperazine;ethane;1-[hex-5-enyl(2-methyltetradecyl)amino]tetradecan-2-ol;3-[2-methylhexadeca-8,10-dienyl(2-methylhexadeca-9,11-dienyl)amino]propane-1-thiolSMILES: CC.CCCCCCCCCCCCC(C)CN(CCCCC=C)CC(CCCCCCCCCCCC)O.CCCCCC=CC=CCCCCCC(C)CN(CCCS)CC(C)CCCCCCC=CC=CCCCC.CCCCN1CCN(CC1)CCCInChIKey: AMOIBCKFWIUEKF-UHFFFAOYSA-NInChI: InChI=1S/C37H69NS.C35H71NO.C11H24N2.C2H6/c1-5-7-9-11-13-15-17-19-21-23-25-27-30-36(3)34-38(32-29-33-39)35-37(4)31-28-26-24-22-20-18-16-14-12-10-8-6-2;1-5-8-11-14-16-18-20-22-24-26-29-34(4)32-36(31-28-13-10-7-3)33-35(37)30-27-25-23-21-19-17-15-12-9-6-2;1-3-5-7-13-10-8-12(6-4-2)9-11-13;1-2/h11,13-18,20,36-37,39H,5-10,12,19,21-35H2,1-4H3;7,34-35,37H,3,5-6,8-33H2,1-2,4H3;3-11H2,1-2H3;1-2H3Synonyms: 1374853-91-4 | 1-butyl-4-propylpiperazine;ethane;1-[hex-5-enyl(2-methyltetradecyl)amino]tetradecan-2-ol;3-[[(8E,10E)-... - Spartalizumab (anti-PD-1), Antibody of programmed cell death 1 (CD279)Associated targets: PDCD1
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Cynomolgus monkey, Human
- Host species: Human
Cas#: 1935694-88-4Synonyms: hPD-1 | Protein PD-1 - Penpulimab (anti-PDCD1), Antibody of programmed cell death 1 (CD279)Associated targets: PDCD1
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Human, Rhesus monkey
- Host species: Human
Cas#: 2350298-92-7Synonyms: Anti-PDCD1 / PD-1 / CD279 Reference Antibody (penpulimab) | Penpulimab | CD279 antibody | CD279 antigen antibody | hP... - Relatlimab (anti-LAG-3/CD223), Antibody of LAG3 (CD223)Associated targets: LAG3
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Cynomolgus monkey, Human
- Host species: Human
Cas#: 1673516-98-7Synonyms: BMS-986016 | RELA | CD223 antibody | CD223 antigen antibody | FDC protein antibody | LAG-3 antibody | Lag3 antibody |... - Sabatolimab (anti-TIM-3), Antibody of TIM3 (CD366)Associated targets: HAVCR2
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Cynomolgus monkey, Human
- Host species: Human
Cas#: 2252262-24-9Synonyms: HAVcr-2 | T-cell immunoglobulin and mucin domain-containing protein 3 | T-cell immunoglobulin mucin receptor 3 | T-ce... - Tremelimumab (anti-CTLA-4), Antibody of cytotoxic T-lymphocyte-associated protein 4 (CD152)Associated targets: CTLA4
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Cynomolgus monkey, Human
- Host species: Human
Cas#: 745013-59-6Synonyms: Tremelimumab | Ticilimumab | CP-675 | 206 | ALPS5 antibody | CD 152 antibody | CD antibody | CD152 antibody | CD152 a... - Enoblituzumab (anti-CD276), Antibody of B7-H3 (CD276)Associated targets: CD276
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Cynomolgus monkey, Human
- Host species: Human
Cas#: 1353485-38-7Synonyms: 4Ig B7 H3 antibody | 4Ig-B7-H3 antibody | AU016588 antibody | B7 H3 antibody | B7 homolog 3 antibody | B7-H3 antibody... - Dostarlimab (anti-PD-1), Antibody of programmed cell death 1 (CD279)Associated targets: PDCD1
- Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Species reactivity（Reacts with): Cynomolgus monkey, Human
- Host species: Human
Cas#: 2022215-59-2Synonyms: CD279 antibody | CD279 antigen antibody | hPD 1 antibody | hPD l antibody | hPD-1 antibody | hSLE1 antibody | PD 1 an...
