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Atipamezole - ≥98% (HPLC), high purity , CAS No.104054-27-5, Antagonist of α 2A-adrenoceptor;Antagonist of α 2B-adrenoceptor;Antagonist of α 2C-adrenoceptor
Basic Description Synonyms MPV1248 | MPV 1248 | PDSP2_001566 | antipamezole | CAS_104054-27-5 | PDSP1_001582 | Atipamezolum (Latin) | Aurin No. 555 | BDBM81807 | AC-1614 | DTXSID2049135 | 4-(2-ethyl-2-indanyl)imidazole. | NCGC00182707-02 | NSC_71310 | Vioxx Dolor | D03002 | FT-0603 Specifications & Purity Moligand™, ≥98%(HPLC) Storage Temp Room temperature Shipped In Normal Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of α 2A-adrenoceptor;Antagonist of α 2B-adrenoceptor;Antagonist of α 2C-adrenoceptor Product Description Atipamezole(MPV1248) is an alpha-adrenoceptor antagonist with high affinity and selectivity for the alpha 2-receptor.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 488184646 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488184646 IUPAC Name 5-(2-ethyl-1,3-dihydroinden-2-yl)-1H-imidazole INCHI InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16) InChi Key HSWPZIDYAHLZDD-UHFFFAOYSA-N Canonical SMILES CCC1(CC2=CC=CC=C2C1)C3=CN=CN3 Isomeric SMILES CCC1(CC2=CC=CC=C2C1)C3=CN=CN3 WGK Germany 3 Alternate CAS 104054-27-5 PubChem CID 71310 MeSH Entry Terms 1H-imidazole, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-;antipamezole;atipamezole;MPV 1248;MPV-1248 Molecular Weight 212.29
Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Melt Point(°C) 129 °C Molecular Weight 212.290 g/mol XLogP3 3.000 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 1 Rotatable Bond Count 2 Exact Mass 212.131 Da Monoisotopic Mass 212.131 Da Topological Polar Surface Area 28.700 Ų Heavy Atom Count 16 Formal Charge 0 Complexity 237.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Safety and Hazards(GHS) WGK Germany 3 Merck Index 861
Citations of This Product 1. Rongzong Qiu, Weifeng Yao, Haocong Ji, Dongdong Yuan, Xiaofeng Gao, Weiping Sha, Fei Wang, Pinjie Huang, Ziqing Hei. (2018) Dexmedetomidine restores septic renal function via promoting inflammation resolution in a rat sepsis model. LIFE SCIENCES, 204 (1). [PMID:29733849 ] [10.1016/j.lfs.2018.05.001 ]
References 1. Rongzong Qiu, Weifeng Yao, Haocong Ji, Dongdong Yuan, Xiaofeng Gao, Weiping Sha, Fei Wang, Pinjie Huang, Ziqing Hei. (2018) Dexmedetomidine restores septic renal function via promoting inflammation resolution in a rat sepsis model. LIFE SCIENCES, 204 (1). [PMID:29733849 ] [10.1016/j.lfs.2018.05.001 ]
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