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(-)-Carveol, mixture of isomers - 97%, high purity , CAS No.99-48-9

  • ≥97%
In stock
Item Number
C102530
Grouped product items
SKUSizeAvailabilityPrice Qty
C102530-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
C102530-10g
10g
9
$43.90
C102530-50g
50g
4
$114.90
C102530-250g
250g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$476.90
View related series
Metabolite (5307)

Basic Description

SynonymsHY-W017370 | p-Mentha-1,8-dien-6-ol | p-Mentha-6, l- | 2-06-00-00102 (Beilstein Handbook Reference) | MFCD00062993 | SCHEMBL56868 | 2-Methyl-5-(1-propen-2-yl)-2-cyclohexenol | 2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ol | FT-0715464 | p-Mentha-1(6),8-di
Specifications & Purity≥97%
Shipped InNormal

Associated Targets(Human)

TRPV3 Tchem Transient receptor potential cation channel subfamily V member 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488180431
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180431
IUPAC Name 2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ol
INCHI InChI=1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3
InChi Key BAVONGHXFVOKBV-UHFFFAOYSA-N
Canonical SMILES CC1=CCC(CC1O)C(=C)C
Isomeric SMILES CC1=CCC(CC1O)C(=C)C
WGK Germany 2
RTECS OS8400000
Molecular Weight 152.23
Reaxy-Rn 1861032
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1861032&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
F1904114Certificate of AnalysisMar 07, 2023 C102530
L2212249Certificate of AnalysisDec 16, 2022 C102530
C2320556Certificate of AnalysisFeb 17, 2022 C102530
C2212407Certificate of AnalysisFeb 17, 2022 C102530
C2212367Certificate of AnalysisFeb 17, 2022 C102530
C2212418Certificate of AnalysisFeb 17, 2022 C102530

Chemical and Physical Properties

SolubilityPartly soluble in water. Soluble in alcohol, ethanol and DMSO.
Refractive Index1.496
Flash Point(°F)208.4 °F
Flash Point(°C)98°C
Boil Point(°C)226-227°C
Molecular Weight152.230 g/mol
XLogP32.100
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass152.12 Da
Monoisotopic Mass152.12 Da
Topological Polar Surface Area20.200 Ų
Heavy Atom Count11
Formal Charge0
Complexity191.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS OS8400000
Reaxy-Rn 1861032
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1861032&ln=

Specifications

Purity(GC)97-100(%)
Refractive index n20/D1.493-1.497
Specific Rotation [a]20/D(c=1 in CHCL3)-130--110(°)
Density (20°C)0.947-0.953
Appearance(c102530)Colorless to Yellow Liquid
Infrared spectrumConforms to Structure

Citations of This Product

1. Xiaojiao Zheng, Weiwei Ma, Qihui Wang, Yaping Xu, Yukun Yang, Shu Qin, Xu Jing.  (2024)  Development of self-dispersion ferrofluid-based dispersive liquid–liquid microextraction for determining chiral fungicide hexaconazole in water, tea, and juice using high-performance liquid chromatography.  MICROCHEMICAL JOURNAL,  196  (109593).  [PMID:8414517] [10.1016/j.microc.2023.109593]
2. Guo-Feng Mao, Xiao-Chang Mo, Hatem Fouad, Ghulam Abbas, Jian-Chu Mo.  (2018)  Attraction behaviour of Anagrus nilaparvatae to remote lemongrass (Cymbopogon distans) oil and its volatile compounds.  NATURAL PRODUCT RESEARCH,      [PMID:28503948] [10.1080/14786419.2017.1326486]
3. Wenbin Xiao, Jiajing Guo, Yanjiao Fu, Zixuan Li, Tongping Zhang, Mingwang He, Ting Liu, Yangbo Xiao, Xuebo Shang, Fuhua Fu, Gaoyang Li, Donglin Su, Zhipeng Gao, Yang Shan.  (2025)  Long-term study of Citrus changshan-huyou Y.B. Chang essential oil: Chemical transformations and their impact on antibacterial efficacy.  FOOD CHEMISTRY,  474  (143118).  [PMID:39908813] [10.1016/j.foodchem.2025.143118]

References

1. Parnas M, Peters M, Dadon D, Lev S, Vertkin I, Slutsky I, Minke B.  (2009)  Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels..  Cell Calcium,  45  (3): (300-9).  [PMID:19135721] [10.1021/op500134e]
2. P L Crowell,W S Kennan,J D Haag,S Ahmad,E Vedejs,M N Gould.  (1992-07-01)  Chemoprevention of mammary carcinogenesis by hydroxylated derivatives of d-limonene..  Carcinogenesis,  13  ((7)): (1261-1264).  [PMID:1638695]
3. M J van der Werf,A M Boot.  (2000-06-01)  Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14..  Microbiology (Reading, England),  146   (( Pt 5)): (1129-1141).  [PMID:10832640]
4. M Wüst,D B Little,M Schalk,R Croteau.  (2001-05-23)  Hydroxylation of limonene enantiomers and analogs by recombinant (-)-limonene 3- and 6-hydroxylases from mint (Mentha) species: evidence for catalysis within sterically constrained active sites..  Archives of biochemistry and biophysics,  387  ((1)): (125-136).  [PMID:11368174]
5. Mitsuo Miyazawa,Masaki Shindo,Tsutomu Shimada.  (2002-01-22)  Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes..  Chemical research in toxicology,  15  ((1)): (15-20).  [PMID:11800592]
6. Mitsuo Miyazawa,Masaki Shindo,Tsutomu Shimada.  (2002-04-16)  Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes..  Drug metabolism and disposition: the biological fate of chemicals,  30  ((5)): (602-607).  [PMID:11950794]
7. Carla C C R de Carvalho,M Manuela R da Fonseca.  (2007-07-10)  Preventing biofilm formation: promoting cell separation with terpenes..  FEMS microbiology ecology,  61  ((3)): (406-413).  [PMID:17617221]
8. S P Bhatia,D McGinty,C S Letizia,A M Api.  (2008-07-22)  Fragrance material review on carveol..  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,  46 Suppl 11  (S85-S87).  [PMID:18640224]
9. Devin R Polichuk,Yansheng Zhang,Darwin W Reed,Janice F Schmidt,Patrick S Covello.  (2010-07-14)  A glandular trichome-specific monoterpene alcohol dehydrogenase from Artemisia annua..  Phytochemistry,  71  ((11-12)): (1264-1269).  [PMID:20621795]
10. Vuy H Li,Abid Mallick,Craig Concannon,Vuy Y Li.  (2011-05-25)  Wide complex tachycardia causing congestive heart failure..  Pacing and clinical electrophysiology : PACE,  34  ((9)): (1154-1157).  [PMID:21605135]
11. Tomoko Iizuka,Yasuhiro Nishikawa,Yoshihiro Mori,Natsuko Zenimura,Takuyuki Matsumoto,Katsutoshi Hiramatsu,Masahiro Komiya.  (2011-06-18)  Artist® tablets (carvedilol) for hypertensive patients in Japan: results of a long-term special survey..  Drugs in R&D,  11  ((2)): (191-205).  [PMID:21679008]
12. M Govindarajan,R Sivakumar,M Rajeswari,K Yogalakshmi.  (2011-12-06)  Chemical composition and larvicidal activity of essential oil from Mentha spicata (Linn.) against three mosquito species..  Parasitology research,  110  ((5)): (2023-2032).  [PMID:22139403]
13. Hiroki Kawasaki,Kotaro Mizuta,Tsugumi Fujita,Eiichi Kumamoto.  (2013-01-29)  Inhibition by menthol and its related chemicals of compound action potentials in frog sciatic nerves..  Life sciences,  92  ((6-7)): (359-367).  [PMID:23352972]
14. Hatice Büşra Konuk,Bengü Ergüden.  (2020-03-21)  Phenolic -OH group is crucial for the antifungal activity of terpenoids via disruption of cell membrane integrity..  Folia microbiologica,  65  ((4)): (775-783).  [PMID:32193708]
15. Imran Malik,Fawad Ali Shah,Tahir Ali,Zhen Tan,Abdullah Alattar,Najeeb Ullah,Arif-Ullah Khan,Reem Alshaman,Shupeng Li.  (2020-07-28)  Potent Natural Antioxidant Carveol Attenuates MCAO-Stress Induced Oxidative, Neurodegeneration by Regulating the Nrf-2 Pathway..  Frontiers in neuroscience,  14  (659-659).  [PMID:32714135]
16. A T Karlberg,K Magnusson,U Nilsson.  (1992-05-01)  Air oxidation of d-limonene (the citrus solvent) creates potent allergens..  Contact dermatitis,  26  ((5)): (332-340).  [PMID:1395597]
17. B M Magnusson,P Runn,L O Koskinen.  (1997-07-01)  Terpene-enhanced transdermal permeation of water and ethanol in human epidermis..  Acta dermato-venereologica,  77  ((4)): (264-267).  [PMID:9228215]
18. W A Duetz,A H Fjällman,S Ren,C Jourdat,B Witholt.  (2001-05-26)  Biotransformation of D-limonene to (+) trans-carveol by toluene-grown Rhodococcus opacus PWD4 cells..  Applied and environmental microbiology,  67  ((6)): (2829-2832).  [PMID:11375201]
19. Aleem U Khand,Andrew C Rankin,William Martin,Jacqueline Taylor,Islay Gemmell,John G F Cleland.  (2003-12-10)  Carvedilol alone or in combination with digoxin for the management of atrial fibrillation in patients with heart failure?.  Journal of the American College of Cardiology,  42  ((11)): (1944-1951).  [PMID:14662257]
20. Marion Kamphoff,Tobias Thiele,Benno Kunz.  (2008-01-16)  Influence of different extraction parameters on a solid-phase dynamic extraction for the gas chromatographic determination of d-limonene degradation products by using a fractional factorial design..  Journal of AOAC International,  90  ((6)): (1623-1627).  [PMID:18193739]
21. Jenna L E Morrish,Andrew J Daugulis.  (2008-03-11)  Inhibitory effects of substrate and product on the carvone biotransformation activity of Rhodococcus erythropolis..  Biotechnology letters,  30  ((7)): (1245-1250).  [PMID:18327538]
22. Jenna L E Morrish,Andrew J Daugulis.  (2008-06-12)  Improved reactor performance and operability in the biotransformation of carveol to carvone using a solid-liquid two-phase partitioning bioreactor..  Biotechnology and bioengineering,  101  ((5)): (946-956).  [PMID:18546419]
23. S P Bhatia,D McGinty,C S Letizia,A M Api.  (2008-07-22)  Fragrance material review on laevo-carveol..  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,  46 Suppl 11  (S88-S90).  [PMID:18640177]
24. Staffan Johansson,Theres Redeby,Timothy M Altamore,Ulrika Nilsson,Anna Börje.  (2009-09-04)  Mechanistic proposal for the formation of specific immunogenic complexes via a radical pathway: a key step in allergic contact dermatitis to olefinic hydroperoxides..  Chemical research in toxicology,  22  ((11)): (1774-1781).  [PMID:19725554]
25. Juan Carlos R Gonçalves,Aron de Miranda H Alves,Anna Erika V de Araújo,Jader Santos Cruz,Demetrius Antônio Machado Araújo.  (2010-07-31)  Distinct effects of carvone analogues on the isolated nerve of rats..  European journal of pharmacology,  645  ((1-3)): (108-112).  [PMID:20670618]
26. Xiaojiao Zheng, Weiwei Ma, Qihui Wang, Yaping Xu, Yukun Yang, Shu Qin, Xu Jing.  (2024)  Development of self-dispersion ferrofluid-based dispersive liquid–liquid microextraction for determining chiral fungicide hexaconazole in water, tea, and juice using high-performance liquid chromatography.  MICROCHEMICAL JOURNAL,  196  (109593).  [PMID:8414517] [10.1016/j.microc.2023.109593]
27. Guo-Feng Mao, Xiao-Chang Mo, Hatem Fouad, Ghulam Abbas, Jian-Chu Mo.  (2018)  Attraction behaviour of Anagrus nilaparvatae to remote lemongrass (Cymbopogon distans) oil and its volatile compounds.  NATURAL PRODUCT RESEARCH,      [PMID:28503948] [10.1080/14786419.2017.1326486]
28. Wenbin Xiao, Jiajing Guo, Yanjiao Fu, Zixuan Li, Tongping Zhang, Mingwang He, Ting Liu, Yangbo Xiao, Xuebo Shang, Fuhua Fu, Gaoyang Li, Donglin Su, Zhipeng Gao, Yang Shan.  (2025)  Long-term study of Citrus changshan-huyou Y.B. Chang essential oil: Chemical transformations and their impact on antibacterial efficacy.  FOOD CHEMISTRY,  474  (143118).  [PMID:39908813] [10.1016/j.foodchem.2025.143118]

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