Immune checkpoint proteins

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  1. Cemiplimab (anti-PD-1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
    • Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    • Species reactivity(Reacts with): Human
    • Host species: Human
    Cas#: 1801342-60-8       
    Synonyms: hPD-1 | Protein PD-1
  2. Pembrolizumab (anti-PD-1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
    • Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    • Species reactivity(Reacts with): Cynomolgus monkey, Human
    • Host species: Human
    Cas#: 1374853-91-4        Compound CID:  168009853
    IUPAC Name: 1-butyl-4-propylpiperazine;ethane;1-[hex-5-enyl(2-methyltetradecyl)amino]tetradecan-2-ol;3-[2-methylhexadeca-8,10-dienyl(2-methylhexadeca-9,11-dienyl)amino]propane-1-thiol
    SMILES: CC.CCCCCCCCCCCCC(C)CN(CCCCC=C)CC(CCCCCCCCCCCC)O.CCCCCC=CC=CCCCCCC(C)CN(CCCS)CC(C)CCCCCCC=CC=CCCCC.CCCCN1CCN(CC1)CCC
    InChIKey: AMOIBCKFWIUEKF-UHFFFAOYSA-N
    InChI: InChI=1S/C37H69NS.C35H71NO.C11H24N2.C2H6/c1-5-7-9-11-13-15-17-19-21-23-25-27-30-36(3)34-38(32-29-33-39)35-37(4)31-28-26-24-22-20-18-16-14-12-10-8-6-2;1-5-8-11-14-16-18-20-22-24-26-29-34(4)32-36(31-28-13-10-7-3)33-35(37)30-27-25-23-21-19-17-15-12-9-6-2;1-3-5-7-13-10-8-12(6-4-2)9-11-13;1-2/h11,13-18,20,36-37,39H,5-10,12,19,21-35H2,1-4H3;7,34-35,37H,3,5-6,8-33H2,1-2,4H3;3-11H2,1-2H3;1-2H3
    Synonyms: 1374853-91-4 | 1-butyl-4-propylpiperazine;ethane;1-[hex-5-enyl(2-methyltetradecyl)amino]tetradecan-2-ol;3-[[(8E,10E)-...
  3. Spartalizumab (anti-PD-1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
    • Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    • Species reactivity(Reacts with): Cynomolgus monkey, Human
    • Host species: Human
    Cas#: 1935694-88-4       
    Synonyms: hPD-1 | Protein PD-1
  4. Penpulimab (anti-PDCD1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
    • Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    • Species reactivity(Reacts with): Human, Rhesus monkey
    • Host species: Human
    Cas#: 2350298-92-7       
    Synonyms: Anti-PDCD1 / PD-1 / CD279 Reference Antibody (penpulimab) | Penpulimab | CD279 antibody | CD279 antigen antibody | hP...
  5. Dostarlimab (anti-PD-1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
    • Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    • Species reactivity(Reacts with): Cynomolgus monkey, Human
    • Host species: Human
    Cas#: 2022215-59-2       
    Synonyms: CD279 antibody | CD279 antigen antibody | hPD 1 antibody | hPD l antibody | hPD-1 antibody | hSLE1 antibody | PD 1 an...
  6. Retifanlimab (anti-PD-1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
    • Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    • Species reactivity(Reacts with): Cynomolgus monkey, Human
    • Host species: Human
    Cas#: 2079108-44-2       
    Synonyms: CD279 antibody | CD279 antigen antibody | hPD 1 antibody | hPD l antibody | hPD-1 antibody | hSLE1 antibody | PD 1 an...
  7. Zimberelimab (anti-PD-1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
    • Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    • Species reactivity(Reacts with): Cynomolgus monkey, Human
    • Host species: Human
    Cas#: 2259860-24-5       
    Synonyms: CD279 antibody | CD279 antigen antibody | hPD 1 antibody | hPD l antibody | hPD-1 antibody | hSLE1 antibody | PD 1 an...
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