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cis-8，11，14-Eicosatrienoic Acid - ≥99%，100mg/ml in ethanol, high purity , CAS No.1783-84-2

In stock
Item Number
C132030
Grouped product items
SKUSizeAvailabilityPrice Qty
C132030-5mg
5mg
2
$22.90
C132030-25mg
25mg
3
$85.90
C132030-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$263.90
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Long-chain polyunsaturated fatty acid

View related series
carboxylic acid (2079) Carboxylic acid capping agent (20) Straight Chain Unsaturated Fatty Acids (2)

Basic Description

SynonymsAS-65384 | cis-8,11,14-Eicosatrienoic acid, >=99% | Dihomo-gamma-linolenate | Dihomo-gamma-linolenic acid | NCGC00161350-03 | (Z,Z,Z)-icosatri-8,11,14-enoate | SR-01000946659 | 20:3(N-6) | 8Z,11Z,14Z-eicosatrienoate | CS-0017463 | GTPL9775 | HMS1361A08 |
Specifications & PurityMoligand™, ≥99%, 100mg/ml in ethanol
Biochemical and Physiological MechanismsLong-chain polyunsaturated fatty acid. Cyclooxygenase and lipoxygenase substrate (IC 50 =45 μM, LTB4 formation). Biosynthetic PGE 1 precursor. Elongase product of γ-linolenic acid. Arachidonic acid analog. Energy source in vivo.
Storage TempProtected from light,Store at -20°C,Argon charged
Shipped InIce chest + Ice pads
GradeMoligand™
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

an ω－6 fatty acid with anti-inflammatory effect

Associated Targets(Human)

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARA Tclin Peroxisome proliferator-activated receptor alpha (9197 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OXER1 Tchem Oxoeicosanoid receptor 1 (131 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Trypsin (394 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RBL-2H3 (1162 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid504763308
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504763308
IUPAC Name (8Z,11Z,14Z)-icosa-8,11,14-trienoic acid
INCHI InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-
InChi Key HOBAELRKJCKHQD-QNEBEIHSSA-N
Canonical SMILES CCCCCC=CCC=CCC=CCCCCCCC(=O)O
Isomeric SMILES CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O
PubChem CID 5280581
Molecular Weight 306.48
Beilstein 1796533

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
B2311943Certificate of AnalysisNov 08, 2024 C132030
B2311928Certificate of AnalysisNov 08, 2024 C132030
L2426196Certificate of AnalysisNov 07, 2024 C132030
B2311502Certificate of AnalysisNov 07, 2024 C132030
B2311949Certificate of AnalysisNov 07, 2024 C132030
B2311929Certificate of AnalysisNov 07, 2024 C132030
G2220588Certificate of AnalysisMay 15, 2024 C132030
G2220516Certificate of AnalysisMay 15, 2024 C132030
I2214131Certificate of AnalysisSep 20, 2022 C132030
G2220515Certificate of AnalysisJun 23, 2022 C132030

Chemical and Physical Properties

SensitivityLight Sensitive,Air Sensitive,Heat Sensitive
Refractive Index1.48
Flash Point(°C)62 °C
Boil Point(°C)200 °C
Molecular Weight306.500 g/mol
XLogP37.200
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count15
Exact Mass306.256 Da
Monoisotopic Mass306.256 Da
Topological Polar Surface Area37.300 Ų
Heavy Atom Count22
Formal Charge0
Complexity327.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count3
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds3
Covalently-Bonded Unit Count1

Specifications

 Specification Sheet

References

1. Vakharia PP, Silverberg JI.  (2018)  New therapies for atopic dermatitis: Additional treatment classes..  J Am Acad Dermatol,  78  (3S1): (S76-S83).  [PMID:29248520] [10.1021/op500134e]

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