Rotaline can induce pulmonary vascular syndrome in rats. This component is known to be toxic and can cause cirrhosis, liver enlargement, sinus syndrome, and right ventricular hypertrophy
Storage Temp
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
Grade
analytical standard
Product Description
Monocrotaline is a macrocyclic compound belonging to the pyrrolizine alkaloid family. This ingredient is found naturally in pig poop beans
1.Haixia Che, Jie Yi, Xiaoting Zhao, Hong Yu, Xianyao Wang, Rui Zhang, Xin Li, Jia Fu, Qian Li. (2023) Characterization of PKCα-rutin interactions and its application as a treatment strategy for PAH by inhibiting ferroptosis. Food & Function, [PMID:38126185][10.1039/D3FO01306E]
2.Yanhui Ge, Shuchang Zhao, Boyi Yuan, Yuan Gao, Ruilin Liu. (2023) In-situ growth of metal coordination-synergistic imprinted polymer onto shrimp shell-derived magnetic FeNi biochar for specific recognition of monocrotaline in herbal medicine. Materials Today Sustainability, 24 (16):(100599). [PMID:3426601][10.1016/j.mtsust.2023.100599]
3.Yang Zhong, Jiayu Gu, Yaoquan Su, Lingzhi Zhao, Yunyun Zhou, Juanjuan Peng. (2022) Real-time screening of hepatotoxins in natural medicine by peroxynitrite responsive lanthanide-based NIR-II luminescent probes. CHEMICAL ENGINEERING JOURNAL, 433 (133263). [PMID:][10.1016/j.cej.2021.133263]
4.Mingyan Ji, Yun Chen, Yifan Ma, Dongping Li, Jin Ren, Hongyue Jiang, Sinuo Chen, Xiaoqing Zeng, Hong Gao. (2024) ADAMTS13 Improves Hepatic Platelet Accumulation in Pyrrolizidine Alkaloids-induced Liver Injury. Journal of Clinical and Translational Hepatology, 13 (1):(25). [PMID:39801786][10.14218/JCTH.2024.00233]
5.Min Fu, Yuan Li, Jingjing Liu, Junjie Liu, Jiaoxia Wei, Yuxin Qiao, Hanxin Zhong, Dongyang Han, Haitao Lu, Li Yao. (2024) Zhishi Xiebai Guizhi Decoction modulates hypoxia and lipid toxicity to alleviate pulmonary vascular remodeling of pulmonary hypertension in rats. Chinese Medicine, 19 (173). [PMID:39696593][10.1186/s13020-024-01039-0]
References
1.Haixia Che, Jie Yi, Xiaoting Zhao, Hong Yu, Xianyao Wang, Rui Zhang, Xin Li, Jia Fu, Qian Li. (2023) Characterization of PKCα-rutin interactions and its application as a treatment strategy for PAH by inhibiting ferroptosis. Food & Function, [PMID:38126185][10.1039/D3FO01306E]
2.Yanhui Ge, Shuchang Zhao, Boyi Yuan, Yuan Gao, Ruilin Liu. (2023) In-situ growth of metal coordination-synergistic imprinted polymer onto shrimp shell-derived magnetic FeNi biochar for specific recognition of monocrotaline in herbal medicine. Materials Today Sustainability, 24 (16):(100599). [PMID:3426601][10.1016/j.mtsust.2023.100599]
3.Yang Zhong, Jiayu Gu, Yaoquan Su, Lingzhi Zhao, Yunyun Zhou, Juanjuan Peng. (2022) Real-time screening of hepatotoxins in natural medicine by peroxynitrite responsive lanthanide-based NIR-II luminescent probes. CHEMICAL ENGINEERING JOURNAL, 433 (133263). [PMID:][10.1016/j.cej.2021.133263]
4.Mingyan Ji, Yun Chen, Yifan Ma, Dongping Li, Jin Ren, Hongyue Jiang, Sinuo Chen, Xiaoqing Zeng, Hong Gao. (2024) ADAMTS13 Improves Hepatic Platelet Accumulation in Pyrrolizidine Alkaloids-induced Liver Injury. Journal of Clinical and Translational Hepatology, 13 (1):(25). [PMID:39801786][10.14218/JCTH.2024.00233]
5.Min Fu, Yuan Li, Jingjing Liu, Junjie Liu, Jiaoxia Wei, Yuxin Qiao, Hanxin Zhong, Dongyang Han, Haitao Lu, Li Yao. (2024) Zhishi Xiebai Guizhi Decoction modulates hypoxia and lipid toxicity to alleviate pulmonary vascular remodeling of pulmonary hypertension in rats. Chinese Medicine, 19 (173). [PMID:39696593][10.1186/s13020-024-01039-0]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
D2503475