Basic Description

Synonyms	(R)-methyl 2-amino-2-phenylacetate, hydrochloride salt \| (R)-2-PHENYLGLYCINE METHYL ESTER HCl \| Benzeneacetic acid, a-amino-, methyl ester, hydrochloride, (aR)- \| BioZate \| H-D-Phg-OMe.HCl \| Methyl (2R)-amino(phenyl)acetate hydrochloride \| H-D-Phg-OMe hyd
Specifications & Purity	≥96%
Shipped In	Normal

Names and Identifiers

IUPAC Name	methyl (2R)-2-amino-2-phenylacetate;hydrochloride
INCHI	InChI=1S/C9H11NO2.ClH/c1-12-9(11)8(10)7-5-3-2-4-6-7;/h2-6,8H,10H2,1H3;1H/t8-;/m1./s1
InChi Key	DTHMTBUWTGVEFG-DDWIOCJRSA-N
Canonical SMILES	COC(=O)C(C1=CC=CC=C1)N.Cl
Isomeric SMILES	COC(=O)[C@@H](C1=CC=CC=C1)N.Cl
WGK Germany	3
PubChem CID	12247453
Molecular Weight	201.65

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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7 results found

Lot Number	Certificate Type	Date	Item
G2017140	Certificate of Analysis	May 07, 2024	P106203
J2229420	Certificate of Analysis	Aug 18, 2022	P106203
J2229447	Certificate of Analysis	Aug 18, 2022	P106203
J2229422	Certificate of Analysis	Aug 18, 2022	P106203
J2229448	Certificate of Analysis	Aug 18, 2022	P106203
C2209240	Certificate of Analysis	May 21, 2022	P106203
C1829003	Certificate of Analysis	Jan 24, 2022	P106203

Chemical and Physical Properties

Specific Rotation[α]	-123° (C=1,H2O)
Melt Point(°C)	189-191°C
Molecular Weight	201.650 g/mol
XLogP3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	201.056 Da
Monoisotopic Mass	201.056 Da
Topological Polar Surface Area	52.300 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	153.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help.
WGK Germany	3

Specifications

Specification Sheet

References

1. K Sasaki,M Satake,T Yasumoto. (1997-11-15) Identification of the absolute configuration of pectenotoxin-6, a polyether macrolide compound, by NMR spectroscopic method using a chiral anisotropic reagent, phenylglycine methyl ester.. Bioscience, biotechnology, and biochemistry, 61 ((10)): (1783-1785). [PMID:9362128]
2. N K Maladkar. (1994-08-01) Enzymatic production of cephalexin.. Enzyme and microbial technology, 16 ((8)): (715-718). [PMID:7765080]
3. M I Youshko,V K Svedas. (2001-02-15) Kinetics of ampicillin synthesis catalyzed by penicillin acylase from E. coli in homogeneous and heterogeneous systems. Quantitative characterization of nucleophile reactivity and mathematical modeling of the process.. Biochemistry. Biokhimiia, 65 ((12)): (1367-1375). [PMID:11173507]
4. Wei Du,Minhua Zong,Yong Guo,Dehua Liu. (2003-05-17) Lipase-catalysed enantioselective ammonolysis of phenylglycine methyl ester in organic solvent.. Biotechnology and applied biochemistry, 38 ((Pt 2)): (107-110). [PMID:12749767]
5. Liu Yang,Dong-Zhi Wei. (2003-09-12) Enhanced enzymatic synthesis of a semi-synthetic cephalosprin, cefaclor, with in situ product removal.. Biotechnology letters, 25 ((14)): (1195-1198). [PMID:12967012]
6. Osamu Shirota,Yukihiro Kaida,Setsuko Sekita. (2004-02-24) [Three dimensional structure analysis of organic chemical compounds from natural sources using NMR spectral analysis].. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, ((121)(121)): (87-88). [PMID:14977004]
7. Esther M Gabor,Dick B Janssen. (2004-08-31) Increasing the synthetic performance of penicillin acylase PAS2 by structure-inspired semi-random mutagenesis.. Protein engineering, design & selection : PEDS, 17 ((7)): (571-579). [PMID:15333773]
8. Alessandro Moretto,Cristina Peggion,Fernando Formaggio,Marco Crisma,Bernard Kaptein,Quirinus B Broxterman,Claudio Toniolo. (2005-08-23) Stereoselective acylation of a racemic amine with C(alpha)-methyl phenylglycine-based dipeptide 5(4H)-oxazolones.. Chirality, 17 ((8)): (481-487). [PMID:16113993]
9. Wen-Yong Lou,Min-Hua Zong,Yu-Ying Liu,Ju-Fang Wang. (2006-03-28) Efficient enantioselective hydrolysis of D,L-phenylglycine methyl ester catalyzed by immobilized Candida antarctica lipase B in ionic liquid containing systems.. Journal of biotechnology, 125 ((1)): (64-74). [PMID:16563544]
10. Sixto Malato,Julián Blanco,Manuel I Maldonado,Isabel Oller,Wolfgang Gernjak,Leonidas Pérez-Estrada. (2007-05-29) Coupling solar photo-Fenton and biotreatment at industrial scale: main results of a demonstration plant.. Journal of hazardous materials, 146 ((3)): (440-446). [PMID:17532127]
11. Sonia Nieto,Palmira Arnau,Elena Serrano,Rafael Navarro,Tatiana Soler,Carlos Cativiela,Esteban P Urriolabeitia. (2009-11-17) Functionalization of methyl (R)-phenylglycinate through orthopalladation: C-Hal, C-O, C-N, and C-C bond coupling.. Inorganic chemistry, 48 ((24)): (11963-11975). [PMID:19911828]
12. Anna Serra,Xavier Domènech,Enric Brillas,José Peral. (2010-11-17) Life cycle assessment of solar photo-Fenton and solar photoelectro-Fenton processes used for the degradation of aqueous α-methylphenylglycine.. Journal of environmental monitoring : JEM, 13 ((1)): (167-174). [PMID:21079836]
13. Y T Liu,S H Lee. (1992-10-01) Production of cephalexin by Gluconobacter oxydans CCRC 10383.. Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 16 ((4)): (184-187). [PMID:1305772]
14. P S Nys,D E Satarova,V B Korchagin,E M Savitskaia. (1981-12-01) [E. coli penicillin amidase. Methods for estimating the close ionization constants of ionogenic groups of the enzyme complex with substrates containing free amino groups].. Antibiotiki, 26 ((12)): (920-932). [PMID:7034639]
15. R Fernández-Lafuente,O Hernández-Jústiz,C Mateo,M Terreni,G Fernández-Lorente,M A Moreno,J Alonso,J L García-López,J M Guisan. (2001-12-26) Biotransformations catalyzed by multimeric enzymes: stabilization of tetrameric ampicillin acylase permits the optimization of ampicillin synthesis under dissociation conditions.. Biomacromolecules, 2 ((1)): (95-104). [PMID:11749160]
16. Wei Du,Min-Hua Zong,Yong Guo,Jun He,Yuan-Yuan Zhang,Zhao-Lin Xie,Wen-Yong Lou. (2002-08-01) [Lipase-catalyzed enantioselective ammonolysis of racemic phenylglycine methyl ester in organic solvent].. Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 18 ((2)): (242-245). [PMID:12148293]
17. Wei Du,Minhua Zong,Yong Guo,Dehua Liu. (2003-07-29) Improving lipase-catalyzed enantioselective ammonolysis of phenylglycine methyl ester in organic solvent by in situ racemization.. Biotechnology letters, 25 ((6)): (461-464). [PMID:12882271]
18. John W Van Klink,Seung-Hwa Baek,Anna J Barlow,Hideki Ishii,Koji Nakanishi,Nina Berova,Nigel B Perry,Rex T Weavers. (2004-08-04) Determination of the absolute configuration of Anisotome irregular diterpenes: application of CD and NMR methods.. Chirality, 16 ((8)): (549-558). [PMID:15290691]
19. Ivan Muñoz,José Peral,José Antonio Ayllón,Sixto Malato,Paula Passarinho,Xavier Domènech. (2006-09-23) Life cycle assessment of a coupled solar photocatalytic-biological process for wastewater treatment.. Water research, 40 ((19)): (3533-3540). [PMID:16989886]

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SKU	Size	Availability	Price
P106203-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$9.90
P106203-25g	25g	6	$28.90
P106203-100g	100g	4	$102.90
P106203-250g	250g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$230.90
P106203-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$415.90

D-phenylglycine methyl ester ·HCl - 96%, high purity , CAS No.19883-41-1