Epinastine HCl - 10mM in DMSO, high purity , CAS No.108929-04-0, Histamine H1 receptor antagonist

  • 10mM in DMSO
In stock
Item Number
E420557
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SKUSizeAvailabilityPrice Qty
E420557-1ml
1ml
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$69.90

Antihistamine. Highly selective, non-sedating H 1 histamine receptor antagonist.

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Compound libraries (12338)

Basic Description

SynonymsEpinastine hydrochloride | 108929-04-0 | Epinastine HCl | Alesion | Elestat | 80012-44-8 | WAL-801CL | WAL 801 CL | Epinastine monohydrochloride | UNII-GFM415S5XL | GFM415S5XL | DE-114 | Epinastine hydrochloride [JAN] | WAL-802-CL | DTXSID1046502 | Epinastine (hydrochloride) | Epinastin
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsEpinastine Hydrochloride is a tetracyclic, histamine H1 receptor antagonist that blocks the release of histamine from mast cells.Antihistamine. Highly selective, non-sedating H 1 histamine receptor antagonist. Mast cell stabilizer used in eye drops to tre
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Action TypeANTAGONIST
Mechanism of actionHistamine H1 receptor antagonist
Product Description

A tetracyclic, histamine H1 receptor antagonist.

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2,4-diazatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine;hydrochloride
INCHI InChI=1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H
InChi Key VKXSGUIOOQPGAF-UHFFFAOYSA-N
Canonical SMILES C1C2C3=CC=CC=C3CC4=CC=CC=C4N2C(=N1)N.Cl
Isomeric SMILES C1C2C3=CC=CC=C3CC4=CC=CC=C4N2C(=N1)N.Cl
WGK Germany 3
RTECS HO4360000
Alternate CAS 80012-44-8,108929-04-0,80012-43-7 (Parent)
PubChem CID 157313
MeSH Entry Terms 3-amino-9,13b-dihydro-1H-benz(c,f)imidazo(1,5a)azepine;epinastine;epinastine hydrochloride;Flurinol;WAL 80;WAL 801;WAL 801 CL;WAL 801CL;WAL-80 Cl
Molecular Weight 285.77

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

SensitivityMoisture & Heat sensitive
Melt Point(°C)275 °C(dec.)
Molecular Weight285.770 g/mol
XLogP3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass285.103 Da
Monoisotopic Mass285.103 Da
Topological Polar Surface Area41.600 Ų
Heavy Atom Count20
Formal Charge0
Complexity378.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2

Safety and Hazards(GHS)

Pictogram(s) GHS06
Signal Danger
Hazard Statements

H301:Toxic if swallowed

Precautionary Statements

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

WGK Germany 3
RTECS HO4360000

Specifications

Solution Calculators

Reviews

Customer Reviews