What is the difference between CD62L and CD62?
CD62L, CD62E, CD62P are two immune cell surface molecules that are members of the selectin family.
CD62L, also known as L-selectin, is an integrin family protein that is mainly expressed on the surface of leukocytes. It is involved in the regulation of leukocyte adhesion and migration, and plays an important role in inflammation and immune response in particular.CD62L helps leukocytes to roll and migrate directionally from the circulation to areas such as sites of inflammation or lymph nodes by binding to its ligands, such as PECAM-1 on vascular endothelial cells.
CD62P, also known as P-selectin, is an adhesion molecule that is primarily expressed on endothelial cells and platelets. During processes such as inflammation and thrombosis, CD62P is rapidly expressed on endothelial cells and binds to ligands (e.g., PSGL-1) on leukocytes, promoting mutual adhesion and activation of leukocytes and platelets.
CD62E, also known as E-selectin, is an adhesion molecule that is mainly expressed on endothelial cells.
For more information, visit our website: www.aladdinsci.com.