Why does nitrobenzene not undergo the Friedel-Crafts acylation reaction?
Why does nitrobenzene not undergo the Friedel-Crafts acylation reaction?
posted this at Jun 5, 2025 Updated at Oct 9, 2023
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Why does nitrobenzene not undergo the Friedel-Crafts acylation reaction?
Because the nitro group on nitrobenzene belongs to a strong passivation group, which has electron absorption induction and conjugation effects, and the density of the π electron cloud on the benzene ring decreases, the Friedel-Crafts acylation reaction will not occur.
