Apoptosis is a tightly regulated cell death mechanism, the core of which is the activation of caspases. Immunofluorescence staining is an effective technique that can simultaneously detect caspases and other apoptosis-related proteins in cell samples.
Apoptosis is a programmed cell death process. Unlike necrosis, apoptosis is an orderly, gene-regulated, and active cell death process. Apoptosis plays an important role in the development of organisms, the maintenance of tissue homeostasis, the regulation of the immune system, and the occurrence ...
The DNA of apoptotic cells is cut into fragments of about 200 base pairs under the action of caspase-activated nuclease (CAD), forming DNA ladders. By detecting DNA fragmentation during apoptosis, the degree of apoptosis can be evaluated.
