The multiple telomere FISH technique described in this chapter is the Chromoprobe Multiprobe-T system developed by Cytocell, which uses a microscope slide divid
Comparative Genomic Hybridization (CGH) is a molecular cytogenetic technique capable of characterizing, in a one-step genome-wide screening procedure, additions
Throughout the history of clinical cytogenetics, G-banding has served as the "gold standard" for detecting total chromosomal abnormalities in clinical samples,
Many of the cationic liposomes used for liposomal transfection of cells in tissue cultures are able to be purchased. Composition optimization is highly dependen
Fanconi anemia (FA) is an autosomal recessive syndrome characterized by progressive bone marrow failure and an increased risk of malignancies, particularly acut
In clinical practice, chromosomal studies require the use of solid tissues other than tumor tissue for one of two reasons: some patients can only obtain solid t
The interstitial center of the villi includes a range of cellular components-fibroblasts, endothelial cells, and macrophages-as well as a large amount of interc
The typing methods described in this unit are needed when there are a large number of samples with multiple microsatellite markers to be typed. For example, a d
