In bioanalytical chemistry, it is very important to isolate organelles to analyze their content or function, which is the basis of many biomedical analyses.
Over the past few decades, magnetic nanoparticles (MNPs) have been increasingly used to separate and differentiate biomolecules, which is the basis of most current molecular diagnostic procedures. The size, morphology, and dispersion of MNPs endow them with specificity, affinity, and binding ...
Small-molecule drugs are variable-specificity drugs targeted within cells, typically well-defined organic substances with a molecular weight of fewer than 900 Daltons, that help regulate biological processes. Due to differences in size, manufacturing, pharmacokinetics, pharmacodynamics, and ...
In gene delivery, vectors are essential in the passage of DNA (hydrophilic, negatively charged) through cell membranes (hydrophobic, negatively charged). In addition, therapeutic efficiency also depends on the efficient delivery of DNA to the target site. Due to the many delivery barriers in the ...