Over the years, oligonucleotide synthesis methods have evolved: from Michelson and Todd's early H-phosphonate and phosphoric acid triglyceride methods, and Khorana's phosphodiester method in the 1950s, to the revisiting of the phosphoric acid triglyceride method in the 1960s and the phosphite ...
Nucleic acid electrophoresis is used in many molecular biology research applications to test experimental results, and sometimes to isolate and purify samples for subsequent applications. Therefore, the application of conventional nucleic acid electrophoresis can generally be divided into ...
