Enzymes-biocatalysts that accelerate intracellular chemical reactions play a vital role in every organism. The catalytic activity of these enzymes has been widely recognized, accelerating the reaction with high specificity and efficiency under mild conditions.
Spirocyclic compounds are not new as an important area of drug research. In recent years, the demand for compounds with high stereospecificity and spatial structure has been increasing, and the introduction of spirocyclic scaffolds has become an innovative strategy in drug design. Spirocyclic ...
