Fmoc-MMAE - 98%, high purity , CAS No.474645-26-6

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Item Number

F647565

Grouped product items
SKU	Size	Availability	Price
F647565-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$200.90
F647565-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$340.90
F647565-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,050.90

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Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC.
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Product Description	Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC Form:Solid IC50& Target:Auristatin

Names and Identifiers

Canonical SMILES	CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35
Isomeric SMILES	CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35
PubChem CID	78358314
Molecular Weight	940.22

Chemical and Physical Properties

Solubility	DMSO : ≥ 45 mg/mL (47.86 mM)
Molecular Weight	940.200 g/mol
XLogP3	7.500
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	23
Exact Mass	939.572 Da
Monoisotopic Mass	939.572 Da
Topological Polar Surface Area	167.000 Å²
Heavy Atom Count	68
Formal Charge	0
Complexity	1620.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	10
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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Basic Description