N-α-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide (FDAA) is a chiral derivatizing agent and is used routinely to improve the detection of underivatized amino acids in high performance liquid chromatography. Its usage is effective in separating stereoisomer.
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Product Description
For derivatization and resolution of amino acids. Derivatized D- and L-amino acids can be resolved and quantitated by HPLC.
1.Pan TANG, Dan HUANG, Kai-Xuan ZHENG, Dan HU, Ping DAI, Chuan-Hui LI, Sheng-Ying QIN, Guo-Dong CHEN, Xin-Sheng YAO, Hao GAO. (2023) Thirteen new peptaibols with antimicrobial activities from Trichoderma sp.. Chinese Journal of Natural Medicines, 21 (1):(868). [PMID:38035942][10.1016/S1875-5364(23)60499-6]
2.Baole Zhang, Wanglong Xu, Chuanlong Yin, Yangming Tang. (2023) Characterization of low-level D-amino acid isomeric impurities of Semaglutide using liquid chromatography-high resolution tandem mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 224 (115164). [PMID:36462248][10.1016/j.jpba.2022.115164]
3.Guo Jing, Cui Jiayi, Xun Mingyue, Zhang Wencheng, Xian Mo, Zhang Rubing. (2025) Constructing Genetically Engineered Escherichia coli for De Novo Production of L-Threo-3-Hydroxyaspartic Acid. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, (1-13). [PMID:40120046][10.1007/s12010-025-05224-1]
4.Wen-Bo Gao, Shu-Ting Xu, Yong-Jie Yan, Cheng Yang, Xiu-Ping Yan. (2025) Kinetic Method Coupled with Thermal-Assisted Paper Spray Ionization Mass Spectrometry for Direct Determination of Enantiomeric Excess of Multiple d/l-Amino Acids in Functional Foods. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 36 (4):(906-913). [PMID:40079893][10.1021/jasms.5c00050]
5.Qingyun Peng, Wenjia Huang, Xiao Zhang, Xiaoyan Pang, Yunan Liu, Wu Ruan, Qun Li, Li Ding, Huizi Jin, Dehua Yang, Junfeng Wang, Ming-Wei Wang. (2025) Structurally Diverse New Metabolites from Three Hadal Trench-Derived Microorganisms. ACS Omega, 10 (6):(6201-6209). [PMID:39989804][10.1021/acsomega.4c11083]
References
1.Pan TANG, Dan HUANG, Kai-Xuan ZHENG, Dan HU, Ping DAI, Chuan-Hui LI, Sheng-Ying QIN, Guo-Dong CHEN, Xin-Sheng YAO, Hao GAO. (2023) Thirteen new peptaibols with antimicrobial activities from Trichoderma sp.. Chinese Journal of Natural Medicines, 21 (1):(868). [PMID:38035942][10.1016/S1875-5364(23)60499-6]
2.Baole Zhang, Wanglong Xu, Chuanlong Yin, Yangming Tang. (2023) Characterization of low-level D-amino acid isomeric impurities of Semaglutide using liquid chromatography-high resolution tandem mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 224 (115164). [PMID:36462248][10.1016/j.jpba.2022.115164]
3.Guo Jing, Cui Jiayi, Xun Mingyue, Zhang Wencheng, Xian Mo, Zhang Rubing. (2025) Constructing Genetically Engineered Escherichia coli for De Novo Production of L-Threo-3-Hydroxyaspartic Acid. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, (1-13). [PMID:40120046][10.1007/s12010-025-05224-1]
4.Wen-Bo Gao, Shu-Ting Xu, Yong-Jie Yan, Cheng Yang, Xiu-Ping Yan. (2025) Kinetic Method Coupled with Thermal-Assisted Paper Spray Ionization Mass Spectrometry for Direct Determination of Enantiomeric Excess of Multiple d/l-Amino Acids in Functional Foods. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 36 (4):(906-913). [PMID:40079893][10.1021/jasms.5c00050]
5.Qingyun Peng, Wenjia Huang, Xiao Zhang, Xiaoyan Pang, Yunan Liu, Wu Ruan, Qun Li, Li Ding, Huizi Jin, Dehua Yang, Junfeng Wang, Ming-Wei Wang. (2025) Structurally Diverse New Metabolites from Three Hadal Trench-Derived Microorganisms. ACS Omega, 10 (6):(6201-6209). [PMID:39989804][10.1021/acsomega.4c11083]
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