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(R)-3-Hydroxybutanoic acid - ≥95%, high purity , CAS No.625-72-9

  • ≥95%
In stock
Item Number
R304188
Grouped product items
SKUSizeAvailabilityPrice Qty
R304188-250mg
250mg
3
$9.90
R304188-1g
1g
2
$18.90
R304188-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$57.90
R304188-10g
10g
1
$83.90
R304188-25g
25g
2
$167.90
R304188-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$469.90

Basic Description

SynonymsQ27075135 | (-)-beta-Hydroxybutyrate, D- | Hydantoin, 5-isobutyl-3-phenyl-2-thio- | 3-D-hydroxybutyric acid | (R)-(-)-3-Hydroxybutyric acid | (R)-(-)-beta-Hydroxybutyric acid | delta-3-hydroxybutyrate | (R)-3-Hydroxybutyric acid | (R)-β-Hydroxybutanoic Ac
Specifications & Purity≥95%
Storage TempStore at 2-8°C,Desiccated
Shipped InWet ice
Product Description

3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. Beta-hydroxybutyrate is a typical partial-degradation product of branched-chain amino acids (primarily valine) released from muscle for hepatic and renal gluconeogenesis.

Associated Targets(Human)

HCAR2 Tclin Hydroxycarboxylic acid receptor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a20 Solute carrier family 22 member 20 (86 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a6 Solute carrier family 22 member 6 (141 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid504756102
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504756102
IUPAC Name (3R)-3-hydroxybutanoic acid
INCHI InChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m1/s1
InChi Key WHBMMWSBFZVSSR-GSVOUGTGSA-N
Canonical SMILES CC(CC(=O)O)O
Isomeric SMILES C[C@H](CC(=O)O)O
Molecular Weight 104.1
Reaxy-Rn 773861
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=773861&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

26 results found

Lot NumberCertificate TypeDateItem
F2214196Certificate of AnalysisApr 02, 2025 R304188
F2214035Certificate of AnalysisApr 02, 2025 R304188
K2425486Certificate of AnalysisNov 12, 2024 R304188
K2425482Certificate of AnalysisNov 12, 2024 R304188
K2425484Certificate of AnalysisNov 12, 2024 R304188
K2425485Certificate of AnalysisNov 12, 2024 R304188
K2425483Certificate of AnalysisNov 12, 2024 R304188
K2425527Certificate of AnalysisNov 12, 2024 R304188
J2409840Certificate of AnalysisSep 21, 2024 R304188
J2409794Certificate of AnalysisSep 21, 2024 R304188
J2409811Certificate of AnalysisSep 21, 2024 R304188
J2409818Certificate of AnalysisSep 21, 2024 R304188
J2409819Certificate of AnalysisSep 21, 2024 R304188
G2429391Certificate of AnalysisJul 09, 2024 R304188
G2429479Certificate of AnalysisJul 09, 2024 R304188
G2429480Certificate of AnalysisJul 09, 2024 R304188
G2429481Certificate of AnalysisJul 09, 2024 R304188
G2429482Certificate of AnalysisJul 09, 2024 R304188
K2307291Certificate of AnalysisOct 21, 2023 R304188
K2307297Certificate of AnalysisOct 21, 2023 R304188
K2307260Certificate of AnalysisOct 21, 2023 R304188
K2307288Certificate of AnalysisOct 21, 2023 R304188
F2214198Certificate of AnalysisMay 30, 2022 R304188
F2214199Certificate of AnalysisMay 30, 2022 R304188
E2325086Certificate of AnalysisMay 30, 2022 R304188
J2310196Certificate of AnalysisMay 30, 2022 R304188

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Chemical and Physical Properties

SolubilitySolubility:H2O: 25 mg/mL (240.15 mM)
SensitivityHeat sensitive
Flash Point(°C)121°C
Boil Point(°C)269.2°C at 760 mmHg
Melt Point(°C)43-50°C
Molecular Weight104.100 g/mol
XLogP3-0.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass104.047 Da
Monoisotopic Mass104.047 Da
Topological Polar Surface Area57.500 Ų
Heavy Atom Count7
Formal Charge0
Complexity69.300
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Reaxy-Rn 773861
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=773861&ln=

Specifications

Appearance(R304188)Colorless or White or Light Yellow Powder or Crystals or solid
Purity(GC)95-100(%)
Specific Rotation [a]20/D(c=1 in MeOH)-25--23(°)
Proton NMR spectrumConforms to structure

Citations of This Product

1. Jingling Guo, Pan Wang, Yifan Cui, Xiaosong Hu, Fang Chen, Chen Ma.  (2023)  Alleviation Effects of Microbial Metabolites from Resveratrol on Non-Alcoholic Fatty Liver Disease.  Foods,  12  (1): (94).  [PMID:36613310] [10.3390/foods12010094]
2. Guojia Yu, Xinjian Chen, Lichao He, Xiangrong Li, Zhiyong Zhou, Zhongqi Ren.  (2021)  Study on the solubilization of telmisartan by forming cocrystals with aromatic carboxylic acids.  CRYSTENGCOMM,  23  (27): (4871-4878).  [PMID:] [10.1039/D1CE00551K]
3. Waqar Uddin, Gang Hu, Xuanxuan Sun, Hui Zhang, Yegui Wang, Lin Hu.  (2020)  Identification of two aromatic isomers between 3- and 4-hydroxy benzoic acid by their perturbation on the potential oscillations of a Belousov-Zhabotinsky system.  Arabian Journal of Chemistry,  13  (1079).  [PMID:] [10.1016/j.arabjc.2017.09.010]
4. Waqar Uddin, Gang Hu, Lin Hu, Yanyang Hu, Zhaohui Fang, Rooh Ullah, Xuanxuan Sun, Yu Zhang, Jimei Song.  (2017)  Identification of two aromatic isomers between 2- and 3-hydroxy benzoic acid by using a Briggs-Rauscher oscillator.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,  803  (135).  [PMID:] [10.1016/j.jelechem.2017.09.014]

References

1. Jingling Guo, Pan Wang, Yifan Cui, Xiaosong Hu, Fang Chen, Chen Ma.  (2023)  Alleviation Effects of Microbial Metabolites from Resveratrol on Non-Alcoholic Fatty Liver Disease.  Foods,  12  (1): (94).  [PMID:36613310] [10.3390/foods12010094]
2. Guojia Yu, Xinjian Chen, Lichao He, Xiangrong Li, Zhiyong Zhou, Zhongqi Ren.  (2021)  Study on the solubilization of telmisartan by forming cocrystals with aromatic carboxylic acids.  CRYSTENGCOMM,  23  (27): (4871-4878).  [PMID:] [10.1039/D1CE00551K]
3. Waqar Uddin, Gang Hu, Xuanxuan Sun, Hui Zhang, Yegui Wang, Lin Hu.  (2020)  Identification of two aromatic isomers between 3- and 4-hydroxy benzoic acid by their perturbation on the potential oscillations of a Belousov-Zhabotinsky system.  Arabian Journal of Chemistry,  13  (1079).  [PMID:] [10.1016/j.arabjc.2017.09.010]
4. Waqar Uddin, Gang Hu, Lin Hu, Yanyang Hu, Zhaohui Fang, Rooh Ullah, Xuanxuan Sun, Yu Zhang, Jimei Song.  (2017)  Identification of two aromatic isomers between 2- and 3-hydroxy benzoic acid by using a Briggs-Rauscher oscillator.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,  803  (135).  [PMID:] [10.1016/j.jelechem.2017.09.014]

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