Recombinant Bovine CD64 Protein, >95% (SDS-PAGE), high purity
Synonyms
CD64 antigen | CD64 | CD64a | Fc fragment of IgG, high affinity Ia, receptor (CD64) | Fc gamma RI | FCG1 | Fc-gamma receptor I B2 | Fc-gamma RI | Fc-gamma RIA | FcgammaRIa | FcgRI | FCGR1 | FcgRIA | FCRI | FcRIA | FLJ18345 | high affinity Ia, receptor for
Grade
Animal Free, Azide Free, Carrier Free
Product Description
Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of asignal peptidethat allows its transport to the surface of a cell, threeextracellularimmunoglobulin domainsof the C2-type that it uses to bind antibody, a hydrophobictransmembrane domain, and a short cytoplasmic tail. CD64 isconstitutivelyfound on only macrophages and monocytes, but treatment of polymorphonuclear leukocyteswith cytokines likeIFNγandG-CSFcan induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.
37.7-52.3 kDa, under reducing conditions; 36.7-51.3 kDa, under non-reducing conditions
Images
Recombinant Bovine CD64 Protein (rp175924) - SDS-PAGE 3 μg/lane of Recombinant Bovine CD64 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 37.7-52.3 kDa under reducing conditions and 36.7-51.3 kDa under non-reducing conditions.
Product Specifications
Shape
Lyophilized
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20°C for 1 year. Avoid freeze / thaw cycle.
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
ZJ24F0303408