| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab190140-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $109.90 | |
| Ab190140-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $519.90 | |
| Ab190140-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,299.90 | |
| Ab190140-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,079.90 |
Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG2SA; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | RG-6125 (anti-Cadherin-11) - Primary antibody, specific to CDH11, Human IgG2SA |
|---|---|
| Synonyms | CAD11 antibody | CAD11_HUMAN antibody | Cadherin 11 antibody | Cadherin 11 type 2 antibody | Cadherin 11 type 2 OB cadherin (osteoblast) antibody | Cadherin-11 antibody | Cdh11 antibody | CDHOB antibody | OB antibody | OB-cadherin antibody | OBcadherin an |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Host species | Human |
| Specificity | CDH11 |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description | RG-6125 (anti-Cadherin-11) is a humanized monoclonal antibody that binds cadherin 11 an adhesion molecule expressed by FLS that is involved in synovial intimal lining aggregation. It has the potential to research FLS-targeted rheumatoid arthritis. |
| Isotype | Human IgG2SA |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
RG-6125 (anti-Cadherin-11) (Ab190140) - ELISA
Immobilized Recombinant Human Cadherin-11 protein at 2.0 μg/mL can bind RG-6125 (anti-Cadherin-11) (Ab190140) with the EC₅₀ of 17.93 ng/mL.
RG-6125 (anti-Cadherin-11) (Ab190140) - SEC
The purity of RG-6125 (anti-Cadherin-11) (Ab190140) is more than 95% verified by HPLC.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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