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Small Molecules & Compound Libraries
Signaling Pathways
Protein Tyrosine Kinase/RTK
Syk
sovleplenib , CAS No.1415792-84-5, Inhibitor of spleen associated tyrosine kinase

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sovleplenib , CAS No.1415792-84-5, Inhibitor of spleen associated tyrosine kinase

Moligand™

CAS#: 1415792-84-5
PubChem CID: 71113742

In stock

Item Number

S613663

Grouped product items
SKU	Size	Availability	Price	Qty
S613663-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
S613663-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,711.90

View related series

Non-receptor Tyrosine Kinase (643) spleen associated tyrosine kinase Inhibitor (20)

Basic Description

Synonyms	CS-0376654 \| GTPL11886 \| SCHEMBL14242080 \| 1415792-84-5 \| (S)-7-(4-(1-(METHYLSULFONYL)PIPERIDIN-4-YL)PHENYL)-N-(MORPHOLIN-2-YLMETHYL)PYRIDO[3,4-B]PYRAZIN-5-AMINE \| EX-A7664 \| Sovleplenib [INN] \| F78019 \| compound 225 [WO2012167733A1] \| Pyrido[3,4-b]pyrazi
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of spleen associated tyrosine kinase

Associated Targets(Human)

SYK Tclin Tyrosine-protein kinase SYK (0 Activities)

Discover Target: SYK

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

INCHI	InChI=1S/C24H30N6O3S/c1-34(31,32)30-11-6-18(7-12-30)17-2-4-19(5-3-17)21-14-22-23(27-9-8-26-22)24(29-21)28-16-20-15-25-10-13-33-20/h2-5,8-9,14,18,20,25H,6-7,10-13,15-16H2,1H3,(H,28,29)/t20-/m0/s1
InChi Key	NJIAKNWTIVDSDA-FQEVSTJZSA-N
Canonical SMILES	CS(=O)(=O)N1CCC(CC1)c1ccc(cc1)c1cc2c(nccn2)c(n1)NC[C@@H]1CNCCO1
Isomeric SMILES	CS(=O)(=O)N1CCC(CC1)C2=CC=C(C=C2)C3=CC4=NC=CN=C4C(=N3)NC[C@@H]5CNCCO5
PubChem CID	71113742

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Molecular Weight	482.600 g/mol
XLogP3	1.200
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	6
Exact Mass	482.21 Da
Monoisotopic Mass	482.21 Da
Topological Polar Surface Area	118.000 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	748.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Specifications

Specification Sheet

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