| Description | Eukaryotic translation initiation factor 2-alpha kinase 1 |
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Gene and Protein Information
| Gene ID | 27102 |
|---|---|
| Uniprot Accession IDs | Q9BQI3 A8K2R2 Q549K6 Q8NBW3 Q9HC02 Q9NYE0 Q9P0V6 Q9P1J5 Q9P2H8 Q9UHG4 |
| Ensembl ID | ENSG00000086232 |
| Symbol | HRI KIAA1369 HCR HRI |
| Chromosome | 7 |
| Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily. |
| Sequence | MQGGNSGVRKREEEGDGAGAVAAPPAIDFPAEGPDPEYDESDVPAEIQVLKEPLQQPTFPFAVANQLLLVSLLEHLSHVHEPNPLRSRQVFKLLCQTFIKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSAKERVRQDPCEDISRIQKIRSREVALEAQTSRYLNEFEELAILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVIQPRADRAAIELPSLEVLSDQEEDREQCGVKNDESSSSSIIFAEPTPEKEKRFGESDTENQNNKSVKYTTNLVIRESGELESTLELQENGLAGLSASSIVEQQLPLRRNSHLEESFTSTEESSEENVNFLGQTEAQYHLMLHIQMQLCELSLWDWIVERNKRGREYVDESACPYVMANVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLACTDILQKNTDWTNRNGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTGLRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQSELFQNSGNVNLTLQMKIIEQEKEIAELKKQLNLLSQDKGVRDDGKDGGVG Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 463255 | EIF2AK1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 9598 | VGNC:7379 | OMA, EggNOG |
| Macaque | 703325 | EIF2AK1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 15467 | Eif2ak1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 10090 | MGI:1353448 | Inparanoid, OMA |
| Rat | 27137 | Eif2ak1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 10116 | RGD:70883 | Inparanoid, OMA |
| Dog | 100302056 | EIF2AK1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 9615 | VGNC:40256 | Inparanoid, OMA, EggNOG |
| Horse | 100062309 | EIF2AK1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 9796 | VGNC:17477 | Inparanoid, OMA, EggNOG |
| Cow | 507689 | EIF2AK1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 9913 | VGNC:28380 | Inparanoid, OMA, EggNOG |
| Opossum | 100027204 | EIF2AK1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 395360 | EIF2AK1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 9031 | CGNC:2470 | Inparanoid, OMA |
| Anole lizard | 100564085 | eif2ak1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 733794 | eif2ak1 | eukaryotic translation initiation factor 2 alpha kinase 1 | 8364 | XB-GENE-962479 | Inparanoid, OMA, EggNOG |
| Zebrafish | 565338 | eif2ak1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 7955 | ZDB-GENE-061013-268 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Eukaryotic translation initiation factor 2-alpha kinase 1
protein / protein kinase / Eukaryotic translation initiation factor 2-alpha kinase 1
protein / transferase / Eukaryotic translation initiation factor 2-alpha kinase 1
protein / kinase / Eukaryotic translation initiation factor 2-alpha kinase 1
protein / non-receptor serine/threonine protein kinase / Eukaryotic translation initiation factor 2-alpha kinase 1
protein / protein kinase / Eukaryotic translation initiation factor 2-alpha kinase 1
protein / transferase / Eukaryotic translation initiation factor 2-alpha kinase 1
protein / kinase / Eukaryotic translation initiation factor 2-alpha kinase 1
DTO Classes
protein / Kinase / Protein kinase / Other group / PEK family / Eukaryotic translation initiation factor 2-alpha kinase 1
protein / Kinase / Protein kinase / Other group / PEK family / Eukaryotic translation initiation factor 2-alpha kinase 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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