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Targets(Human)
MAP3K10

MAP3K10

Description	Mitogen-activated protein kinase kinase kinase 10

Gene and Protein Information

Gene ID	4294
Uniprot Accession IDs	Q02779 Q12761 Q14871
Ensembl ID	ENSG00000130758
Symbol	MLK2 MST MST MLK2 MEKK10
Chromosome	19
Family	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence	MEEEEGAVAKEWGTTPAGPVWTAVFDYEAAGDEELTLRRGDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMCQLSQEKPRVRKRKGNFKRSRLLKLREGGSHISLPSGFEHKITVQASPTLDKRKGSDGASPPASPSIIPRLRAIRLTPVDCGGSSSGSSSGGSGTWSRGGPPKKEELVGGKKKGRTWGPSSTLQKERVGGEERLKGLGEGSKQWSSSAPNLGKSPKHTPIAPGFASLNEMEEFAEAEDGGSSVPPSPYSTPSYLSVPLPAEPSPGARAPWEPTPSAPPARWGHGARRRCDLALLGCATLLGAVGLGADVAEARAADGEEQRRWLDGLFFPRAGRFPRGLSPPARPHGRREDVGPGLGLAPSATLVSLSSVSDCNSTRSLLRSDSDEAAPAAPSPPPSPPAPTPTPSPSTNPLVDLELESFKKDPRQSLTPTHVTAACAVSRGHRRTPSDGALGQRGPPEPAGHGPGPRDLLDFPRLPDPQALFPARRRPPEFPGRPTTLTFAPRPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQPTLLDMDMEGQNQDSTVPLCGAHGSH Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	468880	MAP3K10	mitogen-activated protein kinase kinase kinase 10	9598	VGNC:11235	OMA, EggNOG
Macaque	700477	MAP3K10	mitogen-activated protein kinase kinase kinase 10	9544		Inparanoid, OMA, EggNOG
Mouse	269881	Map3k10	mitogen-activated protein kinase kinase kinase 10	10090	MGI:1346879	Inparanoid, OMA, EggNOG
Rat	308463	Map3k10	mitogen activated protein kinase kinase kinase 10	10116	RGD:1308381	Inparanoid, OMA, EggNOG
Dog	484504	MAP3K10	mitogen-activated protein kinase kinase kinase 10	9615	VGNC:53748	Inparanoid, OMA, EggNOG
Cow		MAP3K10	mitogen-activated protein kinase kinase kinase 10 [Source:HGNC Symbol;Acc:HGNC:6849]	9913		OMA, EggNOG
Pig	100521453	MAP3K10	mitogen-activated protein kinase kinase kinase 10	9823		OMA, EggNOG
Opossum	100017495	MAP3K10	mitogen-activated protein kinase kinase kinase 10	13616		Inparanoid, OMA, EggNOG
Anole lizard	100565973	map3k10	mitogen-activated protein kinase kinase kinase 10	28377		Inparanoid, OMA
Xenopus	100488058	map3k10	mitogen-activated protein kinase kinase kinase 10	8364	XB-GENE-920944	Inparanoid, OMA
Zebrafish	560932	map3k10	mitogen-activated protein kinase kinase kinase 10	7955	ZDB-GENE-050419-112	Inparanoid, OMA

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / TKL group / MLK family / MLK subfamily / Mitogen-activated protein kinase kinase kinase 10

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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