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BRAF

Description	Serine/threonine-protein kinase B-raf

Gene and Protein Information

Gene ID	673
Uniprot Accession IDs	P15056 A4D1T4 B6HY61 B6HY62 B6HY63 B6HY64 B6HY65 B6HY66 Q13878 Q3MIN6 Q9UDP8 Q9Y6T3
Ensembl ID	ENSG00000157764
Symbol	BRAF1 RAFB1 NS7 B-raf BRAF1 RAFB1 B-RAF1
Chromosome	7
Family	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Sequence	MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	463781	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9598	VGNC:14003	OMA, EggNOG
Mouse	109880	Braf	Braf transforming gene	10090	MGI:88190	Inparanoid, OMA, EggNOG
Rat	114486	Braf	B-Raf proto-oncogene, serine/threonine kinase	10116	RGD:619908	Inparanoid, OMA, EggNOG
Dog	475526	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9615	VGNC:38514	Inparanoid, OMA, EggNOG
Horse	100065760	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9796	VGNC:15875	Inparanoid, OMA, EggNOG
Cow	536051	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9913	VGNC:26551	OMA, EggNOG
Pig	100514612	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9823		OMA, EggNOG
Opossum	100024057	BRAF	B-Raf proto-oncogene, serine/threonine kinase	13616		Inparanoid, OMA, EggNOG
Chicken	396239	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9031	CGNC:9744	Inparanoid, OMA
Anole lizard	100556317	braf	B-Raf proto-oncogene, serine/threonine kinase	28377		Inparanoid, OMA
Xenopus	779570	braf	B-Raf proto-oncogene, serine/threonine kinase	8364	XB-GENE-1014202	Inparanoid, OMA
Zebrafish	403065	braf	B-Raf proto-oncogene, serine/threonine kinase	7955	ZDB-GENE-040805-1	Inparanoid, OMA

DTO Classes
protein / Kinase / Protein kinase / TKL group / RAF family / Serine/threonine-protein kinase b-raf

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid