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Targets(Human)
FLT4

FLT4

Description	Vascular endothelial growth factor receptor 3

Gene and Protein Information

Gene ID	2324
Uniprot Accession IDs	P35916 A8K6L4 B5A926 Q16067 Q86W07 Q86W08 VEGFR-3
Ensembl ID	ENSG00000037280
Symbol	VEGFR3 PCL FLT-4 FLT41 LMPH1A LMPHM1 VEGFR3 VEGFR-3
Chromosome	5
Family	Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Sequence	MQRGAALCLRLWLCLGLLDGLVSGYSMTPPTLNITEESHVIDTGDSLSISCRGQHPLEWAWPGAQEAPATGDKDSEDTGVVRDCEGTDARPYCKVLLLHEVHANDTGSYVCYYKYIKARIEGTTAASSYVFVRDFEQPFINKPDTLLVNRKDAMWVPCLVSIPGLNVTLRSQSSVLWPDGQEVVWDDRRGMLVSTPLLHDALYLQCETTWGDQDFLSNPFLVHITGNELYDIQLLPRKSLELLVGEKLVLNCTVWAEFNSGVTFDWDYPGKQAERGKWVPERRSQQTHTELSSILTIHNVSQHDLGSYVCKANNGIQRFRESTEVIVHENPFISVEWLKGPILEATAGDELVKLPVKLAAYPPPEFQWYKDGKALSGRHSPHALVLKEVTEASTGTYTLALWNSAAGLRRNISLELVVNVPPQIHEKEASSPSIYSRHSRQALTCTAYGVPLPLSIQWHWRPWTPCKMFAQRSLRRRQQQDLMPQCRDWRAVTTQDAVNPIESLDTWTEFVEGKNKTVSKLVIQNANVSAMYKCVVSNKVGQDERLIYFYVTTIPDGFTIESKPSEELLEGQPVLLSCQADSYKYEHLRWYRLNLSTLHDAHGNPLLLDCKNVHLFATPLAASLEEVAPGARHATLSLSIPRVAPEHEGHYVCEVQDRRSHDKHCHKKYLSVQALEAPRLTQNLTDLLVNVSDSLEMQCLVAGAHAPSIVWYKDERLLEEKSGVDLADSNQKLSIQRVREEDAGRYLCSVCNAKGCVNSSASVAVEGSEDKGSMEIVILVGTGVIAVFFWVLLLLIFCNMRRPAHADIKTGYLSIIMDPGEVPLEEQCEYLSYDASQWEFPRERLHLGRVLGYGAFGKVVEASAFGIHKGSSCDTVAVKMLKEGATASEHRALMSELKILIHIGNHLNVVNLLGACTKPQGPLMVIVEFCKYGNLSNFLRAKRDAFSPCAEKSPEQRGRFRAMVELARLDRRRPGSSDRVLFARFSKTEGGARRASPDQEAEDLWLSPLTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEILGDLLQGRGLQEEEEVCMAPRSSQSSEEGSFSQVSTMALHIAQADAEDSPPSLQRHSLAARYYNWVSFPGCLARGAETRGSSRMKTFEEFPMTPTTYKGSVDNQTDSGMVLASEEFEQIESRHRQESGFSCKGPGQNVAVTRAHPDSQGRRRRPERGARGGQVFYNSEYGELSEPSEEDHCSPSARVTFFTDNSY Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	462339	FLT4	fms related tyrosine kinase 4	9598	VGNC:6876	OMA, EggNOG
Macaque	716412	FLT4	fms related tyrosine kinase 4	9544		Inparanoid, OMA, EggNOG
Mouse	14257	Flt4	FMS-like tyrosine kinase 4	10090	MGI:95561	Inparanoid, OMA, EggNOG
Rat	114110	Flt4	fms-related tyrosine kinase 4	10116	RGD:621737	Inparanoid, OMA, EggNOG
Dog	481464	FLT4	fms related tyrosine kinase 4	9615	VGNC:40910	Inparanoid, OMA, EggNOG
Horse	100066773	FLT4	fms related tyrosine kinase 4	9796	VGNC:18069	Inparanoid, OMA, EggNOG
Cow	338031	FLT4	fms related tyrosine kinase 4	9913	VGNC:29044	OMA, EggNOG
Pig	100518179	FLT4	fms related tyrosine kinase 4	9823		OMA, EggNOG
Opossum	100032078	FLT4	fms related tyrosine kinase 4	13616		Inparanoid, EggNOG
Chicken	395742	FLT4	fms related tyrosine kinase 4	9031	CGNC:49452	Inparanoid, OMA, EggNOG
Anole lizard	100556373	flt4	fms related tyrosine kinase 4	28377		Inparanoid, OMA
Xenopus	100493801	flt4	fms related tyrosine kinase 4	8364	XB-GENE-483183	Inparanoid, OMA, EggNOG
Zebrafish	30121	flt4	fms-related tyrosine kinase 4	7955	ZDB-GENE-980526-326	Inparanoid, OMA

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / TK group / VEGFR family / Vascular endothelial growth factor receptor 3

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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