| Description | Multidrug resistance protein 1 |
|---|
Gene and Protein Information
| Gene ID | 5243 |
|---|---|
| Uniprot Accession IDs | P08183 A8K294 B5AK60 Q12755 Q14812 |
| Ensembl ID | ENSG00000085563 |
| Symbol | MDR1 PGY1 CLCS MDR1 P-GP PGY1 ABC20 CD243 GP170 |
| Chromosome | 7 |
| Family | Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. |
| Sequence | MDLEGDRNGGAKKKNFFKLNNKSEKDKKEKKPTVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRSDINDTGFFMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTAGNEVELENAADESKSEIDALEMSSNDSRSSLIRKRSTRRSVRGSQAQDRKLSTKEALDESIPPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIGVFTRIDDPETKRQNSNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQAGTKRQ Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 463516 | ABCB1 | ATP binding cassette subfamily B member 1 | 9598 | VGNC:4240 | OMA, EggNOG |
| Macaque | ABCB1 | multidrug resistance protein 1 [Source:RefSeq peptide;Acc:NP_001028059] | 9544 | Inparanoid, EggNOG | ||
| Mouse | 18671 | Abcb1a | ATP-binding cassette, sub-family B (MDR/TAP), member 1A | 10090 | MGI:97570 | Inparanoid, OMA, EggNOG |
| Rat | Abcb1b | ATP-binding cassette, subfamily B (MDR/TAP), member 1B [Source:RGD Symbol;Acc:3318] | 10116 | OMA, EggNOG | ||
| Horse | 100034074 | ABCB1 | ATP binding cassette subfamily B member 1 | 9796 | VGNC:14907 | Inparanoid, OMA |
| Cow | 281585 | ABCB1 | ATP binding cassette subfamily B member 1 | 9913 | Inparanoid, OMA | |
| Opossum | 100027288 | LOC100027288 | multidrug resistance protein 1 | 13616 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / serine protease / Multidrug resistance protein 1
protein / cysteine protease / Multidrug resistance protein 1
protein / serine protease / Multidrug resistance protein 1
protein / cysteine protease / Multidrug resistance protein 1
DTO Classes
protein / Transporter / ATP-binding cassette transporter family / ABCB subfamily / Multidrug resistance protein 1
protein / Transporter / ATP-binding cassette transporter family / ABCB subfamily / Multidrug resistance protein 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
|---|