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Recombinant Human IGF-I/IGF-1 Protein

Features and benefits
  • Accession #: P05019
  • Bioactivity: Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is typically 28.6 ng/mL.
  • Endotoxin Concentration: <1.0 EU/μg
In stock
Item Number
rp156332
Grouped product items
SKUSizeAvailabilityPrice Qty
rp156332-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$56.90
rp156332-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
rp156332-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
rp156332-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$213.90

Carrier Free, ≥90% (SDS-PAGE), Active, E. coli, No tag, 49-118 aa

Basic Description

Product NameRecombinant Human IGF-I/IGF-1 Protein
SynonymsIBP1 | IGF1 | IGF-1 | IGF1A | IGFI | IGF-I | IGF-IA | IGF-IB | insulin-like growth factor 1 (somatomedin C) | insulin-like growth factor 1 | insulin-like growth factor I | insulin-like growth factor IA | insulin-like growth factor IB | Mechano growth fact
GradeActiBioPure™, Bioactive, Carrier Free, High Performance
Specifications & PurityCarrier Free, Bioactive, ActiBioPure™, High Performance, ≥90%(SDS-PAGE), See COA
Biochemical and Physiological MechanismsInsulin-like growth factor 1 (IGF-1 or IGF-I), also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. Human IGF-1 is synthesized as two precursor isoforms with N- and alternate Cterminal prop
BioactivityMeasured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is typically 28.6 ng/mL.
Endotoxin Concentration<1.0 EU/μg
Amino Acids49-118 aa
SequenceGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
Accession #P05019
Predicted molecular weight7.7 kDa
SDS-PAGE10.2 & 13.8 kDa, under reducing conditions; 10.4 & 13.8 & 20.9 kDa, under non-reducing conditions.

Images

Recombinant Human IGF-I/IGF-1 Protein (rp156332) - Bioactivity
Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is typically 28.6 ng/mL.

Recombinant Human IGF-I/IGF-1 Protein (rp156332) - SDS-PAGE
3 μg/lane of Recombinant Human IGF-I/IGF-1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 10.2 & 13.8 kDa under reducing conditions and 10.4 & 13.8 & 20.9 kDa under non-reducing conditions.
IGF-I/IGF-1 can form oligomers under certain conditions (PMID: 11551198).

Product Specifications

ConcentrationSee COA
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.1 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20°C for 1 year. Avoid freeze/thaw cycle.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Specifications

Solution Calculators

Reviews

Customer Reviews